Received: DecemAccepted: JPublished: August 23, 2022Ĭopyright: © 2022 Zahroh et al. Stock, The University of Edinburgh Usher Institute of Population Health Sciences and Informatics, UNITED KINGDOM (2022) Factors influencing appropriate use of interventions for management of women experiencing preterm birth: A mixed-methods systematic review and narrative synthesis. Most included studies were from high-income countries (37/46 studies), which may affect the transferability of these findings to low- or middle-income settings.Ĭitation: Zahroh RI, Hazfiarini A, Eddy KE, Vogel JP, Tunçalp Ӧ, Minckas N, et al. Women reported hesitancy in accepting interventions, as they typically learned about them during emergencies. We identified a range of barriers influencing appropriate use of the 4 interventions globally, which include the following: inaccurate gestational age assessment, inconsistent guidelines, varied knowledge, perceived risks and benefits, perceived uncertainties and constraints in administration, confusion around prescribing and administering authority, and inadequate stock, human resources, and labour and newborn care.

We included 46 studies from 32 countries, describing factors affecting use of ACS (32/46 studies), tocolytics (13/46 studies), magnesium sulphate (9/46 studies), and antibiotics (5/46 studies). Behaviour change models (Theoretical Domains Framework Capability, Opportunity, and Motivation (COM-B)) were used to map barriers and facilitators affecting appropriate use of these interventions. We used an iterative narrative synthesis approach to analysis, assessed methodological limitations using the Mixed Methods Appraisal Tool, and assessed confidence in each qualitative review finding using the GRADE-CERQual approach. Eligible studies explored perspectives of women, partners, or community members who experienced preterm birth or were at risk of preterm birth and/or received any of the 4 interventions, health workers providing maternity and newborn care, and other stakeholders involved in maternal care (e.g., facility managers, policymakers). We searched MEDLINE, EMBASE, CINAHL, Global Health, and grey literature from inception to. We conducted a mixed-methods systematic review including primary qualitative, quantitative, and mixed-methods studies.

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